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Manufacturing Services

Contained Roller Compaction

Roller compaction is a proven process that provides a method of granulation for materials that are heat and moisture sensitive. The process avoids the use of granulation liquids and high temperatures associated with wet granulation and subsequent drying methods.

Roller compaction turns powder blends into densified sheets using the pressure of two compacting rollers. The resulting sheets can then be milled to any desired mesh size providing an efficient and scalable process. PCI has invested in a contained Gerteis Mini-Pactor to further expand our contained manufacturing operations. This technology offers a patented proven design able to process highly potent molecules using effective containment technology and integrated cleaning systems.

Our investment in the Gerteis Mini-Pactor allows easy scale-up to commercial volumes, with an output range from 10 grams per trial to 100kg/hr, facilitating shorter and less costly development programs. The addition of this state-of-the-art technology to our already award-winning contained operations, ensures that PCI is able to offer the full range of processing options for the development and manufacture of highly potent molecules. Ongoing investments in our facility ensures that we continue to lead the market in contained processing.

Our dedicated team of specialists will be happy to discuss any of your Contained Roller Compaction needs. Contact us on +1 815-484-1528 (US) or +44 1495 713 633 (UK) or email sales@pciservices.com


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